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From the American College of Rheumatology

Rheumatology for Primary Care
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Sarcoidosis Case Studies

Home » Sarcoidosis Case Studies
Sarcoidosis Case Studies

Answer: Obtain chest x-ray

Patient is presenting with erythema nodosum and has periathritis of her ankles. High suspicion for Lofgrens syndrome, and a chest x-ray would be the next best step to check for any hilar lymphadenopatontent.

Answer: Obtain cardiac MRI

Patients with sarcoidosis commonly have asymptomatic heart involvement, but sarcoid can affect any part of the heart, most commonly presenting with conduction abnormalities. Sudden death caused by heart block or ventricular arrhythmias is the most feared complication. Cardiac MRI and cardiac FDG-PET scans are highly sensitive and specific in the assessment of patients with cardiac sarcoidosis suspected by clinical symptoms or screenings tests.

  • Case 1

  • Case 2

  • Case 1

A 73 yo F with hx of well-controlled hypothyroidism presented to the Ed, as she was found down, unconscious near a café.

She was successfully resuscitated after requiring emergency treatment for sudden cardiac arrest.

Echocardiogram revealed severe biventricular failure with inferior posterior septal wall motion abnormality. A heart catherization was performed, which showed mild non-obstructive coronary artery disease.

What is the next best step?

  1. Monitor on telemetry
  2. Start aspirin
  3. Obtain cardiac MRI
  4. Call cardiac electrophysiology consult
Show Next Step
  • Case 2

A 37 yo F with hx of well-controlled asthma on albuterol prn presented with an erythematous, nonpruritic rash of 1 week duration on her legs and new onset of joint pains. Two days prior to her ER visit, she noted bilateral, left greater than right, ankle pain, redness and swelling. She was afebrile with normal heart rate, blood pressure, and oxygen saturation on room air.

Physical exam was notable for erythematous painful nodules scattered on her lower legs. Ankles had full range of motion with erythema and diffuse soft tissue swelling. No effusion was palpated in joint. Laboratory data revealed elevated inflammatory markers.

What is the next best step?

  1. Start corticosteroids
  2. Discharge patient with dermatology followup
  3. Obtain chest x-ray
  4. Obtain ankle x-rays
Show Next Step
View Information About Sarcoidosis
pcp2312024-02-16T04:02:27+00:00

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This product was funded by a medical grant from Pfizer. The content was written by a physician work group. See Authors.

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